can prednisone cause muscle weakness

Corticosteroid-Induced Myopathy: Background, Pathophysiology

Frequency: muscle weakness usually affects patients treated for several weeks with high doses of corticosteroids. In some conditions this is due to reduced blood and nutrient supply to muscles: Peripheral

arterial disease : this is caused by narrowing of the arteries, usually due to the build-up of cholesterol. Study of skeletal muscle glycogenolysis and glycolysis in chronic steroid myopathy, non-steroid histochemical type-2 fiber atrophy, and denervation. Disease process that causes weakness mainly to the proximal muscles of the. Smoking causes narrowing of the arteries, leading to peripheral arterial disease. Physical, chronic (classic) steroid myopathy physical findings are as follows: Proximal muscle weakness is more pronounced than is distal muscle weakness; however, severe relative weakness of the anterior tibialis muscle can be found. Localised pain is the primary symptom but weakness also results. An excess of exogenous corticosteroid can result from steroid. People with fibromyalgia tend to complain more of the pain than the tiredness or weakness. Finally, people with diabetes also have an increased tendency to narrowing of the arteries (see 'Peripheral arterial disease above). Process that causes weakness mainly to the proximal muscles of the. Previous Differential Diagnoses Askari A, Vignos PJ Jr, Moskowitz. This is an expected side-effect which anyone on long-term treatment is likely to experience. Some rare muscular dystrophies : these can present in adulthood and include Charcot-Marie-Tooth syndrome and the facioscapulohumeral dystrophies. Although not all of these side effects may occur, if they do occur they may need medical attention. Fluorinated steroids seem to produce weakness and myopathy more frequently than do nonfluorinated ones. Some of these conditions respond well to steroids (which need to be taken for many months before the condition resolves). Chronic reviews kidney disease : this affects the whole body environment, both through an imbalance of the salts in the body and through a possible effect on calcium and vitamin D levels.

weakness, cause, muscle, prednisone | Category: Aburaihan, Akrihin

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This leads to easy tiring when you try to do things that would have been easier when the muscles were fit. There are many possible causes of muscle weakness. Chronic pain : a general effect on energy levels can result from chronic pain. 10, some case reports describe the development of muscle weakness after the administration of a single dose of corticosteroid. Previous systemic corticosteroid use does not appear to contribute to the development of myopathy. Muscle damage through injury There are many ways in which your muscles can be directly damaged. Electrolyte disorders and lack of fluid in the body (dehydration) Problems of the balance of salts in the body, including dehydration through not drinking enough, cause muscle tiredness. They may want to watch you walk. Underactive thyroid (hypothyroidism) In this condition a shortage of thyroid hormone leads to generalised tiredness. It can progress to permanent changes if the medicines are not stopped.